CATIS-ICAD Phase III
(2025)Objective
To determine whether combination antithrombotic therapy is superior to aspirin alone in preventing recurrent stroke in patients with intracranial atherosclerotic disease.
Study Summary
• The trial is investigating whether aspirin alone or aspirin plus low dose rivaroxaban improves outcomes in stroke patients with intracranial atherosclerosis..
Intervention
Low-dose rivaroxaban (2.5mg bid) plus aspirin vs. aspirin alone, initiated within 7 to 100 days of the index event.
Inclusion Criteria
Patients aged ≥40 years with acute ischemic stroke or high-risk transient ischemic attack due to ICAD.
Study Design
Arms: Aspirin vs. Aspirin + Rivaroxaban
Patients per Arm: Not specified in given information
Outcome
• Pending results..