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This week in the neurology world — approvals, policy, liability, conferences, and notable reads.

Week of July 12, 2026 · 21 items
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FDA Approves First Gene Therapy for Young Children with Sickle Cell Disease
Drugs & FDAFDA · fda.gov · Jul 1
The U.S. Food and Drug Administration today issued a supplemental approval for Casgevy (exagamglogene autotemcel) for patients aged 2 years and older with either sickle cell disease (SCD) with…
Large Registry Study Questions Utility of Plasma CGRP as Diagnostic Biomarker for Migraine
Drugs & FDANeurologyLive · neurologylive.com · Jul 12
In a cross-sectional analysis of more than 1700 participants, plasma CGRP concentrations did not distinguish individuals with migraine from healthy controls, suggesting limited utility as a…
Looking Beyond Gene Therapy for Treating Charcot-Marie-Tooth Disease: Carla Taveggia, PhD
Drugs & FDANeurologyLive · neurologylive.com · Jul 11
The director of the Division of Neuroscience at IRCCS Istituto Ortopedico Rizzoli discussed why targeting shared biologic pathways, rather than individual mutations, may represent a promising…
Active Smoking Associated With Doubled Relapse Rate in MOGAD
Drugs & FDANeurologyLive · neurologylive.com · Jul 11
An Oxford study found that current smokers with MOGAD had a 2.2-times higher annualized relapse rate than never smokers, while past smokers showed no elevated risk, supporting smoking cessation as…
AAIC 2026 Preview: David Wolk, MD, on Biomarkers, Disease Heterogeneity, and What's Next in Alzheimer Research
Drugs & FDANeurologyLive · neurologylive.com · Jul 10
Ahead of the 2026 Alzheimer's Association International Conference, David Wolk, MD, discusses the meeting's biggest scientific themes, from plasma biomarkers and disease-modifying therapies to…
Roche ends 2 Huntington’s disease programs, including Ionis-partnered tominersen
Drugs & FDAFierceBiotech · fiercebiotech.com
Roche has halted development on two of its Huntington’s disease prospects, marking another blow for a patient community that has long awaited new medicines.
GSK cuts losses on $700M upfront Alzheimer’s collab with Alector following 2 clinical failures
Drugs & FDAFierceBiotech · fiercebiotech.com
GSK has walked away from a $2.2 billion biobucks neurodegenerative disease pact with Alector that has seen both “next generation” drugs involved flunk clinical trials.
Satellos’ ‘intriguing’ Duchenne data raise hopes ahead of key readout
Drugs & FDAFierceBiotech · fiercebiotech.com
Satellos Bioscience has shared evidence that its Duchenne muscular dystrophy drug candidate is active in adults, leading analysts to predict the molecule “could re-imagine the ... therapeutic…
Rapid Stroke Blood Test Gets FDA Breakthrough Device Status
Drugs & FDAWeill Cornell · news.cornell.edu · Jul
The FDA granted Breakthrough Device Designation to NSE-FAST, the first rapid blood test to aid diagnosis of acute ischemic stroke (measuring neuron-specific enolase); a pivotal trial is planned for late 2026.
No Note About Patient Refusal of Test Before Missed Cancer
Medico-legalHarvard CRICO · rmf.harvard.edu · Jun 4
A delay in following a patient’s right kidney mass was complicated by the patient’s refusal of a CT scan and the providers’ incomplete and conflicting documentation of patient education and…
Fatal Team Failure to Widen the Diagnostic Focus
Medico-legalHarvard CRICO · rmf.harvard.edu · Mar 3
The entire care team was faulted for poor fetal monitoring — an escalation and diagnostic-focus failure that ended in a fatal outcome, a lesson in shared responsibility.
Missed Protocols, Medication Mix-up, Patient Death
Medico-legalHarvard CRICO · rmf.harvard.edu · Jan 12
A nursing medication error compounded by missed protocols led to a patient death — how handoff gaps and system failures cascade into harm.
Neurology Claims: A Malpractice Risk Review
Medico-legalThe Doctors Company · thedoctors.com · Feb
A 2026 review of neurology malpractice claims centered on failures in intraoperative neuromonitoring supervision and communication during spinal surgery.
Hospital ACOs raised Medicare spending 0.8% under ACO REACH: 8 notes
Healthcare SystemBecker's Hospital Review · beckershospitalreview.com · Jul 10
Health system-led standard ACOs increased Medicare spending by 0.8% over ACO REACH’s first three years, while ACOs built around independent physician practices cut spending by the same 0.8%, a…
A Look at 1115 Waiver Evaluations for Medicaid Payments to Institutions of Mental Disease (IMD) for Substance Use Disorder
Healthcare SystemKFF · kff.org · Jul 9
As SUD IMD waiver evaluations and renewals are becoming available, states face a shifting Medicaid and policy and waiver landscape. This brief examines findings from the first available summative…
Digital Health Tools and Technologies: An Overview of CMS’ Recent Efforts to Expand Their Use in Medicare
Healthcare SystemKFF · kff.org · Jul 7
As an increasing share of older adults have adopted digital health technologies over the past several years, and with most expressing interest in using them to manage their health care, the…
Vermont Becomes First State to Ban Paraquat, a Parkinson’s-Linked Weed Killer
Healthcare SystemAP News · apnews.com · Jun 25
Vermont became the first U.S. state to ban paraquat, one of the most-used herbicides, citing a possible link to Parkinson’s disease — as the EPA continues its safety review and the manufacturer phases out production.
CMS Proposes 2027 Physician Payment Rule
FinancialCMS · cms.gov · Jul 14
CMS’s proposed CY2027 Medicare Physician Fee Schedule (July 14, 2026) modernizes physician payment and shifts toward value — with a projected ~1.2–1.7% conversion-factor cut; comments close Sept 14.
Physician Compensation Report 2026: Pay Up ~3% to $386K
FinancialMedscape · medscape.com · 2026
Average U.S. physician pay rose about 3% to ~$386,000; eight specialties now top $500K (orthopedics leads at $611K) and ENT crossed $500K for the first time.
The Quiet Corruption of Medical Research
Interesting ReadsDoximity Op-Med · opmed.doximity.com · Jul 9
Graduation Day: A Poem
Interesting ReadsDoximity Op-Med · opmed.doximity.com · Jul 9
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